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Regular use of drugs like Viagra
Researchers in British Columbia say they've found a "strong" link between use of drugs that treat erectile dysfunction and a handful of serious eye conditions.To get more news about 正品犀利士哪裡買, you can visit our official website.
A study conducted through the University of British Columbia's faculty of medicine suggested the risk of developing three serious conditions increased by as much as 85 per cent for regular users of drugs like Viagra and Cialis.
Those conditions include serous retinal detachment, the collection of fluid behind the retina with no tears or breaks. Those who have SRD experience the sudden appearance of spots or "floaters" in their field of vision and may see flashes of light, UBC said.Ischemic optic neuropathy (ION) is another of the conditions, in which there is a compromised blood supply to the optic nerve resulting in loss of vision. The third is retinal vascular occlusion (RVO), a condition that results in sudden loss or blurring of vision as well as dark spots due to a blood clot in the veins or arteries of the retina.
Two of the three conditions were already linked to two of the three conditions, the school said in a news release Thursday, but only anecdotally, through case studies.
The latest peer-reviewed research, published in the journal JAMA Ophthalmology this week, was the first large epidemiological study. It confirmed the links, UBC said.
The study involved the health insurance claims of 213,033 U.S. men. These men had no history of the eye conditions in the year before they started regularly using an ED medication, UBC said.
Researchers tracked the men's claims to see how many of them developed the above eye conditions, and how it compared to those who didn't use any ED drugs on a regular basis.
They then factored in statistics on conditions known to be tied to eye problems – such as diabetes and coronary artery disease – and found that ED medication users were 2.58 times more likely to develop SRD.
They were 2.02 times more likely to experience ION, according to their insurance claims, and 1.44 times more likely to develop RVO.
"These are rare conditions, and the risk of developing one remains very low for any individual user," Mahyar Etminan said in the UBC statement.
But, the associate professor in the school's ophthalmology and visual sciences department went on, given an estimated 20 million prescriptions are doled out each month in the U,S., it could still impact a significant number of people.The drugs work by improving blood flow. As described by the U.S.-based Mayo Clinic, the drugs reverse ED by "enhancing the effects of nitric oxide, a natural chemical your body produces that relaxes the muscles in the penis. This increases blood flow and allows you to get an erection in response to sexual stimulation."
But it's also known, according to Etminan, that drugs like Viagra, Levitra, Staxyn and Cialis can hinder blood flow to other parts of the body.
"So although our study doesn't prove cause-and-effect, there is a mechanism by which these medications could conceivably lead to these problems," the associate professor said.
The ION risk is known from other research, but the possible risk of the conditions SRD and RVO are not addressed in the information given to patients, UBC said.
Etminan said he hopes his team's research will raise awareness of all the potential side effects, and that patients will then let their doctors know if they note any visual changes.
Other possible side effects of oral ED medications include flushing, headache, indigestion, stuffy or runny nose, back pain and, again as described by the Mayo Clinic, "visual changes, such as blue tinge to vision, sensitivity to light or blurred vision."
Puyi: The last emperor of China
On 16 August 1945, the emperor of Manchukuo, Aisin Gioro Puyi, was with his family at the airport in Shenyang, about to escape to Japan on board a Japanese military aircraft, when he was detained by the Soviet Red Army and sent to be incarcerated in the Soviet Union as a WWII Allied prisoner of war.To get more news about empress wanrong, you can visit shine news official website.
After thousands of years of the imperial system, Puyi was the very last emperor of China. His difficult life was a symbol of China’s fate and the enormous changes happening in the world.
In August 1945, after Japan surrendered, Emperor Puyi of Manchukuo was detained by the Soviet Red Army while preparing to board a plane to escape to Japan, and sent to the Soviet Union.
The Qing dynasty was the last of China’s dynasties. It was established by the minority Manchurians, a nomadic group from northeast China, and was one of China’s most powerful dynasties. China’s current territory is generally inherited from the Qing dynasty.
The history of the Manchurians is closely intertwined with that of China. Its people became powerful in the early 12th century and defeated the Song dynasty, occupied northeast China and established the Jin dynasty, which they saw as a legitimate dynasty of China. They gradually assimilated the Han ethnic culture, but a century later were driven back to the northeast by the Mongol empire. Subsequently, the Mongols were defeated by the Han-led Ming dynasty; 200 years later, the Ming dynasty grew weak and the Manchurians rose again, with outstanding political and military leaders, to establish the state of Qing. In 1644, the Qing army invaded China and occupied the whole of it within 40 years, including Taiwan.
In 1792, Britain’s King George III sent George Macartney, 1st Earl Macartney as a special envoy leading a large delegation to China. He declined to kowtow when meeting the Emperor Qianlong according to the rules of the Chinese imperial court, sparking diplomatic friction. With rich text records and hand-drawn images by the British delegation on their return, Britain and the Western world had a deep impression of China and the Emperor Qianlong, who came to symbolise the power and authority of the Chinese emperors.
An etching of the British delegation meeting Emperor Qianlong by British artist William Alexander. On 8 September 1793, the delegation finally reached Rehe, and met the emperor on 14 September. On the right is Macartney, while Qianlong is seated in the raised sedan. This scene is drawn from imagination; in fact, Qianlong was in a tent in the middle, where the British delegation entered for an audience.
An image by British artist William Alexander showing the British delegation finally reaching the borders of China, where they see a Chinese military outpost. The soldiers are mostly armed with bows and arrows and long swords, and the image also shows the Qing dynasty's elite force, the “tiger soldiers”, on the left.
An image by British artist William Alexander showing the Great Wall, on the way from Beijing to Rehe. The delegation was held spellbound by this grand man-made edifice, and Macartney wrote in his journal: “If the other parts of it be similar to those which I have seen, it is certainly the most stupendous work of human hands.” Alexander never saw the Great Wall, but drew this imposing section of the wall winding upwards through the mountains near Gubeikou based on his companions’ descriptions, as if he saw it for himself.
A picture by British artist William Alexander showing senior Chinese officials heading out on a colourful dedicated vessel with luxurious fittings. The flag on the vessel shows the rank of the officials, and civilian vessels would generally make way for official vessels.
On the other hand, the Qing royal family were people from the grasslands, good travellers and strong fighters. Under the first three emperors, Mongolia, Xinjiang and Tibet became part of China, making it a huge, multi-ethnic empire. The Manchurians saw themselves as the legitimate successors of the Chinese dynasty. They forced the Hans to adopt Manchurian hairstyles and dressing, while they themselves switched to Han writing and language and customs, as well as institutions and systems. Nevertheless, the Manchurians were a minority group, having long-term conflicts with the majority Han population. Han resistance groups in southern China often put out calls to “oppose the Qing dynasty and restore the Ming”.
In the mid- to late 19th century, under bombardment from the guns and cannons on modern vessels owned by the rising Western maritime powers, the Chinese empire seemed as old and frail as many ancient empires. It was forced to keep ceding territory and pay reparations and was on the brink of crumbling, and was painfully humiliated. The Chinese Revolutionary Party led by Sun Yat-sen took the slogan “Expel the Tatars” — a call to drive out the Manchurians and restore Han rule. Many Manchurian officials became targets of attack and assassination, striking fear among them for a time.
How to Get Viagra: Do You Need A Prescription?
Well, it’s definitely a conversation you'd never be able to have with anyone except a board-certified healthcare professional, because Viagra isn't available over the counter. And that blue pill in the ad you clicked on probably isn’t a Viagra pill at all.To get more news about where to buy VIAGRA, you can visit our official website.
We know, it's a bummer. But it makes sense. Viagra (and its generic version and active ingredient, sildenafil) is one of the most popularly prescribed medications for erectile dysfunction on the market today — but the key word there is "prescribed."
In the United States, both brand name Viagra and its generic version sildenafil are only sold to people with a valid prescription.
We’ve explained why Viagra can only be purchased with a prescription and how you can get a prescription to use it. We also get into why attempting to buy Viagra without a prescription — or ordering non-prescription Viagra “alternatives” — isn’t worth the time, hassle or potential health issues.
Do You Need a Prescription for Viagra?
Straight answer: Yes. FDA-approved since the late 1990s, Viagra (and sildenafil) is a prescription-only medication.
Other ED medications, including tadalafil (Cialis®), vardenafil (Levitra®) and avanafil (Stendra®) are also only available with a valid prescription in the United States.
Laws regarding the sale of Viagra vary in other countries. For example, Viagra is available over the counter in the United Kingdom as Viagra Connect®. If you’re located outside the United States, you can check your local laws for more information about the availability of ED medications.
Why Can’t I Buy Viagra Without a Prescription?
Sildenafil belongs to a class of medications called PDE5 inhibitors. It works by blocking the effects of an enzyme called phosphodiesterase type 5, or PDE5, which regulates blood flow to your penis. As you can imagine, anything you put into your body that can affect the way your blood flows — especially in such an impactful way — probably shouldn’t be handled lightly.
With great power comes great responsibility, right?
For most men, Viagra works as a safe and effective medication that treats erectile dysfunction without causing any major issues. However, like all medications, Viagra has the potential to cause side effects.
Most of these side effects are mild and will gradually resolve with time, but some side effects can be more serious, which is a big reason Viagra is only available with a prescription.
Viagra and other erectile dysfunction medications can also interact with other drugs, including a few used to treat common cardiovascular health issues.
Some of these interactions can be fatal. Let us say it again. Some of these interactions can be fatal.
That’s another reason Viagra is only available by prescription. Because higher dosages can increase the risk of experiencing adverse effects, it's important to have a healthcare provider monitor your dosage, with an eye on side effects and drug interactions.
Buying Viagra Online in 2023
What is Viagra?
Viagra is the brand name version of sildenafilTrusted Source.To get more news about where to buy VIAGRA, you can visit our official website.
Doctors usually prescribe Viagra to help relieve erectile dysfunction (ED), which causes a person to have difficulty getting or maintaining an erection.
Following sexual stimulation, taking Viagra helps increaseTrusted Source blood flow to the penis, which can help individuals maintain an erection for sexual intercourse. However, doctors do not recommend taking more than one dose of Viagra daily.
This drug can start working within 30 minutes, and its effects can last 4 hours. Although doctors usually prescribe 50 milligrams (mg) of Viagra, they may lower this to 25 mg or increase it to 100 mg.
How to get Viagra safely online
People can purchase Viagra online from several online pharmacies and telehealth companies.
However, the drug is only available with a prescription. Some online pharmacies can fill an electronic prescription and notify the person when Viagra is available for collection at their local pharmacy. Other online pharmacies offer delivery to the person’s door.
If an individual does not have a current prescription, some online pharmacies and telehealth companies may offer an online consultation with a doctor via a phone or video call. This consultation may lead to the doctor prescribing Viagra, which the company can fill.However, people should never purchase Viagra from companies that do not require a prescription. There is a possibility that companies will sell products that do not contain the ingredients they should.
For example, a 2020 study found that 60%Trusted Source of vardenafil the researchers looked at was falsified and inauthentic, containing other PDE5 inhibitors.
The World of Work for Women in China
For the first time in 60 years, China’s population is shrinking. As the average age of China's working-age population continues to rise, encouraging childbearing has become the new bellwether, and this is bringing about a change for China’s working women. A number of cities have introduced complementary measures to encourage childbearing, focusing on granting of child-care subsidies and new parental leave. But are these policies making things better?To get more news about traditional chinese women, you can visit shine news official website.
Traditional barriers
Influenced by Chinese philosopher Confucius, a notable feature of East Asian societies has been the different status of genders. Historically, women in China were required to obey their fathers' orders when unmarried and their husbands' orders after marriage; they had no choice or say in family life and lacked the right to inherit family names and property. And they certainly weren't in control of their own work life or careers. The world of work has since opened up for women in China, but there is still some way to go.
Even after industrialisation over the past four decades, traces of the gender divide remains in these Confucius-influenced cultures. Based on the Global Gender Gap Report 2022 by the World Economic Forum, China ranked No.102, compared with other prominent Asian economies, such as South Korea at No.99 and Japan in No.116.
This gap is reflected in salaries in China. According to the 2022 survey on the current situation of Chinese women in the workplace published by Zhaopin, a Chinese recruitment platform, the average monthly salary of Chinese women in the workplace is 8,545 yuan. This is 12% lower than the men's average monthly salary of 9,776 yuan.
They also face a glass-ceiling. Out of 100 employed women, only about 34 hold management positions compared with about 41 of men (per 100 employed). There is also a perception problem regarding women's ability. Only 5.7% of workers rated women as "strong leaders", compared with 51.5% for men.
Women also face extreme pressures relating to their physical appearance. Facial anxiety was reported in more than 61.5% of women in the workplace, compared with 35.4 % of men. When asked whether appearance can affect a women’s career development, 82.2% of working women and 77.3% of working men in China agreed. Women still suffer from unfair ’higher requirements’ that don't apply to men. This focus on appearance is reflected in Chinese CVs where almost all companies require a picture of the applicant to be attached.
Improvements in education
However, despite this gap, rapid economic development has helped to undermine some of the patriarchal social structures in China. Historically, only Chinese men were able to take part in the imperial examinations – the elite examinations which determined access to government office.
In contemporary China, this has changed dramatically, with women now receiving the same access to education as men (though parents with more than one child may still prioritize sons, especially in more rural areas). According to the 2022 data from Zhaopin, Chinese working women are more highly educated than men, with 55.9 % of women having a bachelor's degree or above, much higher than the 33.6 % for men.
How to Work With Blocks in AutoCAD
Blocks are—quite literally—the building blocks of AutoCAD. Recently, Sheen In Liew and Sophia Lee of the AutoCAD team hosted an in-depth webinar to help you learn how to work with blocks in AutoCAD.To get more news about download cad, you can visit shine news official website.
Here, we’ll share some of the key insights from this AutoCAD blocks tutorial along with links to take you directly to the topic and follow along with the webinar video.
What Are Blocks in AutoCAD?
If you’re starting at the very beginning, this is a great introduction to blocks, definitions, and what they can help you do. You can go straight to the video and learn more about the basics of blocks.
How to Create a Block in AutoCAD
Now that you have an understanding of blocks, you can learn how to create your own blocks in AutoCAD. In the example used in the webinar, a simple workflow is demonstrated for a dynamic title block.
Learn how to create a block definition and how to modify the definition using the Block Editor. Within the block editor, you’ll also discover some extremely useful functionalities such as attributes and dynamic block features, including base point, stretch, and more.
How to Save a Block in AutoCAD
Once you’ve gone through the steps of creating a block, you can save it to use for projects and drawings in the future. You’ll find some great tips and step-by-step instructions of how to save a block in AutoCAD within the video.
There are also some useful block features that you can find in AutoCAD Express Tools, which are only available in AutoCAD and not AutoCAD LT. Discover these block and Express Tool tips in the video.
Finally, it’s time to learn how to count blocks in AutoCAD. There are three ways to count blocks: BCOUNT command for AutoCAD, Select Similar, and QSELECT for AutoCAD LT. Here’s how it can be done with examples in the video.
Águilas y Chivas mantienen paridad en choques de semifinales
El Clausura 2023 está en su recta final y en una de las semifinales tendremos el Clásico nacional, donde se enfrentarán los dos equipos más populares y ganadores del balompié azteca: el América y Chivas.To get more news about Futbol Mexicano, you can visit our official website.
Este duelo ya es atractivo por sus protagonista, pero tiene un extra agregado debido a que estará en juego el boleto a la final del campeonato, por lo que las expectativas son altas.
No será la primera vez que estos dos clubes se enfrenten en unas semifinales, al contrario, será la quinta ocasión que se midan en la antesala de la final.Las Águilas y el Rebaño se han visto las caras en las semifinales cuatro veces y el saldo es de dos triunfos para cada bando. La primera fue en la temporada 1982-1983, en la que los azulcremas se llevaron la ida por 2-1, pero en la vuelta los rojiblancos se impusieron con un contundente 3-0, para finalmente avanzar a la final, que terminaron perdiendo con el Puebla.
Para la campaña 1990-1991 se volvieron encontrar en esta ronda y los de Coapa no encontraron rival y barrieron a los tapatíos con un 5-0 global. Aunque los capitalinos no pudieron completar la obra y fueron superados por los Pumas en la final.
La tercera semifinal disputada entre los dos se dio en el Apertura 2006. El Rebaño sagrado ganó la ida 2-0 y en la vuelta igualaron sin goles. En esa ocasión el Guadalajara sí redondeó la temporada con el título, tras superar al Toluca en la última ronda.
Por último, el Clausura 2007 fue la última vez que América y Chivas se disputaron el pase a la final. Los capitalinos ganaron los dos partidos 1-0, aunque nuevamente no logró levantar la copa y fue superado por el Pachuca.
Ahora, después de 14 años vuelven a disputarse el pase a la final. En el papel, las Águilas son ligeramente favoritas que las Chivas, debido a que en la jornada 12 de la fase regular se enfrentaron y en la cancha del Estadio Akron y los de Coapa se impusieron 4-2. Además finalizaron un lugar arriba en la tabla general, aunque tras lo mostrado en los cuartos de final, donde ambos sufrieron para calificar.
Los azulcremas superaron al Atlético de San Luis, aunque los potosinos llegaron a estar a un gol de eliminarlos; mientras que los rojiblancos eliminaron al Atlas solo por su mejor posición en la general, es decir, no fueron capaces de vencer en el global a los Zorros.
Al final todo se definirá en dos encuentros, uno el jueves en el Akron y la vuelta el próximo domingo en el Azteca, para definir al equipo que se enfrentará con Monterrey o Tigres por el título de la Liga MX.
Chivas vs América Hora y Canal para ver EN VIVO semifinal Liga MX
Tras el fin de semana la Liga MX confirmó a los cuatro equipos que siguen en pie por el torneo Clausura 2023.To get more news about Liga MX Tabla, you can visit our official website.
Chivas y América se enfrentarán en un clásico nacional que asegurará el tiquete a la final para uno de los dos equipos.
Le puede interesar: Liga Mx: fechas y horarios confirmados para los partidos de semifinales
El Rebaño Sagrado, consiguió su pase a semifinales tras eliminar a Atlas en el clásico tapatío, el cuadro de Paunovic logró igualar la serie en casa y terminó clasificando por haber ocupado un mejor lugar en la tabla general de la Liga MX.
Por otro lado, América sufrió en casa contra San Luis, los potosinos lograron dos goles que igualaban la serie a tres goles, sin embargo, las Águilas encontraron un gol que les dio la tranquilidad de clasificar a semifinales.
Está claro que no es la primera vez que se enfrentan en la Liguilla, sin embargo, la última vez que se cruzaron en estás instancia fue en una ocasión muy particular por lo que significó para los mexicanos, pues el país y el mundo enfrentaban la pandemia.
El partido de ida entre el Rebaño y las Águilas será el próximo jueves 18 de mayo a las 20:10 horas del centro y podrá verse por Canal 5, TUDN y TV Azteca.
Binance slams US crypto crackdown and makes bid for UK oversight
Binance, the world’s largest cryptocurrency exchange, has said a crackdown on crypto has made it “very difficult” to do business in the US, adding that it now hopes to be regulated in the UK.To get more news about BINANCE, you can visit wikifx.com official website.
Patrick Hillmann, the company’s chief strategy officer, said at the Financial Times’ crypto and digital assets summit that the US “has been very confusing over the past six months”. He pointed to the Securities and Exchange Commission’s actions against rival exchange Coinbase over alleged securities laws violations as a sign of how “the US right now is in this weird place”.
In contrast with his comments that it was now a “very difficult time” to do business in the US, Hillmann said Binance would do “everything we possibly can” to be regulated in the UK.
Binance had previously clashed with London regulators who said the exchange was incapable of being regulated after it failed to provide basic information about its business activity. The group has no fixed headquarters and offers services around the world.
In 2021, the Financial Conduct Authority ordered the company to stop all regulated activities in Britain, and last year a joint venture partner said the company had filed a “grossly inaccurate” annual report for one of its UK subsidiaries.
Hillman declined to confirm whether the company had reapplied to the FCA’s registration regime for crypto businesses, which covers companies’ processes to prevent money laundering and terrorism financing.
Other groups have claimed that UK officials have been overly wary of fintech and crypto companies. This week, the head of payments company Revolut blamed “extra cautious” UK regulators for delays in gaining its banking licence.
Binance has been the target of US regulators clamping down on perceived illicit activity this year.
In March. the Commodity Futures Trading Commission brought a lawsuit against the group, alleging it had been operating illegally in the country and had broken the law by extensively soliciting US customers. At the time, Binance called the CFTC complaint “unexpected and disappointing”.
The Department of Justice also named Binance as a counterparty to Bitzlato, a crypto exchange whose founder was charged with transmitting millions of illicit crypto funds in violation of US money-laundering regulations.
Binance’s US affiliate, Binance US, last month abandoned a proposed $1bn deal for the assets belonging to Voyager Digital, a crypto lender that fell into bankruptcy last year.
Hillmann said the “broader regulatory pivot we’ve seen in the US” was different from Binance’s discussions with the CFTC. However he played down the threat of US enforcement actions on the company and the industry, saying: “I expect at some point the US is going to want to pivot and play catch-up to Europe, which just passed Mica [the EU’s crypto asset regulation], which is a huge step forward.”
The EU legislation is intended to provide a framework for regulating crypto assets in the bloc, so giving greater certainty to consumers and market participants.
The Binance enforcement case is one of many brought by US regulators against some of the biggest companies in the crypto industry.
Among them, Nasdaq-listed Coinbase is the focus of an SEC investigation into possible securities laws violation. Crypto payments company Ripple is also engaged in a long-running lawsuit brought by the SEC in 2020 alleging it violated securities laws.
Top 5 Books to Learn About Blockchain
Innovative blockchain technology works without the need for a central authority. Blockchain is the underlying technological foundation of cryptocurrencies, such as Bitcoin and Ethereum. Dozens of leading financial firms, including Goldman Sachs (GS) and JPMorgan (JPM), are investing heavily in developing the technology. For people who want to learn more about blockchain technology and its applications, here are three of the best books on the subject.To get more news about learn blockchain, you can visit wikifx.com official website.
Burniske and Tatar look at blockchain from a financial perspective, but they also cover key technological concepts along the way. "Cryptoassets: The Innovative Investor's Guide to Bitcoin and Beyond" is written for investors, rather than programmers or Bitcoin enthusiasts. That keeps most of their explanations relevant and comprehensible. Burniske and Tatar start with the origins of Bitcoin during the 2008 financial crisis and cover the basics. They also explain the crucial differences between Bitcoin and broader blockchain technology. The book then goes into detail on the types of cryptoassets that have arisen, such as crypto tokens and crypto commodities.
This book also goes far beyond most of the rest of the literature by attempting to define cryptoassets as an asset class. There is even a chapter that takes on the difficult task of developing a valuation framework for cryptoassets. While the market is still too young for any framework to be definitive, Burniske and Tatar deserve praise for laying the necessary foundations. Finally, they also deal with the practical details of blockchain investing. Blockchain wallets, cryptocurrency exchanges, and initial coin offerings (ICOs) are all covered.
The father and son team of Don and Alex Tapscott have written "Blockchain Revolution" to explain the impact of cryptocurrencies. The fully open platform of blockchain technology will expand and transform what we can do online, the way we do it, and who can participate. According to the Tapscotts, blockchain technology will immensely improve the delivery of expanding financial services and the safeguarding of personal identity information. Blockchain also has benefits for business contracts and the development of the Internet of Things (IoT).
The book also discusses the various ways that blockchain technology is changing the future of money, transactions, and business. Don Tapscott, also the author of "Wikinomics," and his son, Alex, an expert on the blockchain, carefully explain the technology. They see it as a simple but transformative protocol that enables financial transactions to be both anonymous and secure through the distributed ledger. The authors recognize that blockchain technology is still in its infancy. They do an excellent job of separating what the technology can actually deliver now from its vast potential for the future.
Blockchain technology and Bitcoin are linked because blockchain made cryptocurrencies possible. This book offers the writings of the mysterious creator of Bitcoin, known as Satoshi Nakamoto. As of early 2020, the general public still did not know the true identity of Nakamoto.
The Nakamoto persona has only a virtual existence, much like its cryptocurrency creation. The persona is present only in the online publications Nakamoto offered to explain Bitcoin during the earliest days of its introduction. The Book of Satoshi is a definitive collection of Nakamoto's essential writings, including the original paper detailing the idea of Bitcoin. The book also contains Nakamoto's explanation of how Bitcoin works and a chronologically organized collection of emails and online forum posts by Nakamoto.
Antony Lewis, formerly of early cryptocurrency exchange itBit, has been an expert in the cryptocurrency and blockchain spaces for nearly a decade. In this book, Lewis clearly and concisely breaks down technical aspects of blockchain technology in a way that is digestible and understandable for those within and outside of the space. While this book also covers the fundamentals of cryptocurrencies as well, it is also a useful guide for those particularly interested in blockchain technology and its many applications.
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