freemexy's blog
I have not really tried centrophenoxine that much since getting ME/CFS (I did try it in the early years of my ME/CFS, but that was some time ago, and I don't remember what it's effects were on my brain fog).
Piracetam 800 mg is currently my nootropic of choice for reducing brain fog, and it works quite well for me. But I only take it when I really need to concentrate hard on something, because unfortunately I find piracetam creates an undesirable emotional flatness side effect. Other ME/CFS patients have also reported this same emotional flatness side effect of piracetam. Emotional flatness is of course on of the ME/CFS symptoms listed in the CCC, and I suffer from this symptom anyway, so I don't really want anything which exacerbates it.
So perhaps I should try centrophenoxine again, because if it works as well as piracetam, but does not have the piracetam emotional flatness side effects, centrophenoxine would be a useful treatment for brain fog.
Like the many highly-driven, Soylent-chugging residents of Silicon Valley, I too was looking for brain food that would bring my attention and memory sharply in line. Ideally, it would have to be a nootropic that I could obtain easily, without a prescription, and it wouldn’t cause any side effects like Modafinil or Adderall do. I had used Sunifiram sporadically to very pleasant effects, but gave it up because of safety concerns (it hasn’t been tested on humans).Coluracetam powder
At this point I stumbled across a Coluracetam review online that called it the next best nootropic that would likely become very popular in the coming years. It had undergone trials and the results were positive in light of its potential for treating anxiety and depression.
What is known?
This particular brain candy belongs to a group of nootropics called racetam, derived from the one that started it all – Piracetam, go read our piracetam review. BrainCells Inc. now has the patent for the drug and they have been conducting research on it. Phase 2A trials have found it promising for general anxiety and Major Depressive Disorder. Some studies suggest that it may be particularly good for enhancing areas of the brain that deal with visual processing.
My experience has been very pleasant and interesting to say the least. I had read that responses to nootropics are very individual. For instance, some people find Phenylpiracetam enhances problem solving and creative thought, but a friend used it only to experience light brain fog. I took this supplement with no expectations, but I was very pleasantly surprised at the effect it had on me.
Within a few hours of taking the first dose, I experienced a sharp clearing of vision and alertness. The effect was similar to what I had experienced with Sunifiram. It seemed very powerful, and I could actually feel the effects of the drug. The effects also lasted for around three to four hours. There was a slight, not unpleasant pressure at the temples accompanied by better moods, some increase in the color saturation of what I was seeing, and when I got down to work with it, I was definitely able to recall the words I was looking for a lot better. My memory also improved for that duration – I was able to remember stuff from books way more extensively than ever before, this as well as the activity of the working- and short term memory increased.
With more extended use, I realized that unlike Sunifiram (which is not a racetam like Coluracetam) it offered a calmer and more possessed thought process. Personally, the laid-back alertness of of this supplement suits me, though it may not be enough for people who want a nervy, super-speedy thought process. The only downside of Coluracetam for me is that its effects last for only a few hours.
CRL-40,940 CAS 90280-13-0 FLMODAFINIL
CRL-40,940 powder
also referred to as smart drugs, memory enhancers, neuro enhancers,
cognitive enhancers, and intelligence enhancers, are drugs, supplements,
nutraceuticals, and functional foods that purportedly improve mental
functions such as cognition, memory, intelligence, motivation,
attention, and concentration. Greenway biotech produce kinds of
Nootropics ,nootropics are thought to work by altering the availability
of the brain's supply of neurochemicals (neurotransmitters, enzymes,
andhormones), by improving the brain's oxygen supply, or by stimulating
nerve growth.
Basic details of CRL-40,940:
Product Name: CRL-40,940
CAS No.:90280-13-0
Other Names: BisfluoroModafinil / FlModafinil / Fladrafinil
MF:C15H13F2NO2S
EINECS No.:N/M
Place of Origin:ShenZhen, China (Mainland)
Type:Vitamins, Amino Acids and Coenzymes
Grade Standard:Medicine Grade
Usage: Nootropics API
Brand Name: SENDI
Purity:99%min
Grade:Phamaceutical Grade
Appearance:White Powder
Assay:99.0~101.0%
Certificate:GMP/ISO9001
CAS:90280-13-0
Shelf life:2 Years
Application:Pharmaceutical Raw Intermediates
Factory:YES
Molecular structure:
The claims range from design defects and failure to warn about the potentially dangerous complications testosterone could cause, to negligence and breach of warranty, both express and implied. Other claims include false marketing efforts, such as marketing testosterone treatments for off-label uses not approved by the U.S. Food and Drug Administration (FDA). Specific claims were made in each individual lawsuit, as various people have experienced different problems with testosterone therapy.
Testosterone Products and Companies Being Sued
AndroGel testosterone lawsuits have been extremely high-profile, given the large number of cases filed against AbbVie Inc., a division of Abbott Laboratories. However, a number of other products and companies have also found themselves at the heart of legal claims. Companies like Endo Pharmaceuticals, GlaxoSmithKline, Actavis, and Eli Lilly and Company have all been named as defendants in these suits. Some of the TRT products under litigation are no longer available on the market.
Uses for Aniracetam
Classified as a smart drug, Aniracetam powder is typically used in alternative medicine to sharpen memory, improve concentration, and increase mental alertness. In addition, aniracetam is sometimes used for the following conditions:
Although few clinical trials have tested the health effects of aniracetam, a number of preliminary studies indicate that aniracetam may offer certain health benefits.
In a report published in the journal CNS Drug Reviews in 2002, for instance, investigators analyzed the available research on the use of aniracetam in the treatment of central nervous system (CNS) disorders and disease states.
Looking at findings from animal-based studies, the researchers found that aniracetam shows promise in the management of conditions like posttraumatic stress disorder, attention-deficit hyperactivity disorder, autism, and sleep disorders.
However, the report's authors note that is currently "no convincing evidence" of aniracetam's effectiveness in treating any of these conditions in humans. Here's a look at several other key findings from the available studies on aniracetam:
Anxiety
Aniracetam may aid in the treatment of anxiety disorders, according to a 2001 study published in the European Journal of Pharmacology. In tests on mice, researchers found that aniracetam may help alleviate anxiety by affecting a number of neurotransmitters (a class of chemicals involved in carrying messages from nerve cells to other cells).
Depression
Aniracetam may possess antidepressant-like effects, a 2001 study from the journal Psychopharmacology suggests. In tests on rats, scientists discovered that aniracetam may help stimulate the release of dopamine (a neurotransmitter commonly found at low levels in people with depression).
Cognitive Impairment
Several preliminary studies have shown that aniracetam may be of some benefit to people with cognitive impairment. For example, a 2012 study published in CNS Neuroscience & Therapeutics found that treating elderly adults with aniracetam for a year led to a significant improvement in cognitive function. Involving 276 older adults with cognitive disorders, the study also found that aniracetam had beneficial effects on mood and emotional wellbeing.
In addition, a rat-based study published in Psychiatry and Clinical Neurosciences in 2000 found that aniracetam may help treat the sleep disturbances commonly associated with dementia.
Applications:
Belviq is a serotonin 2C receptor agonist. It hasbeen shown to decrease food consumption and promote satiety by selectivelyactivating serotonin 2C receptors in the brain.
Belviq is specifically indicated as an adjunct to a reduced-calorie diet andincreased physical activity for chronic weight management in clinically obeseadults (BMI of 30 kg/m2 or greater) and overweight adults (BMI of 27 kg/m2 orgreater) with at least one weight-related comorbid condition.
Belviq is supplied as a tablet designed for oral administration. The recommendeddose is one 10mg tablet twice daily. Use of Belviq should be discontinued if 5%weight loss is not achieved by week 12 of treatment.
As with many fellow S10 reviewers, I’ve been using the Buds for about a week now. They happily hitched a ride in my ears from San Francisco to Barcelona and then back home to New York. And I’ve been digging them the whole time.
This certainly isn’t Samsung’s first wireless earbud rodeo, but frankly, it took the company taking more than a few pages out of Apple’s playbook to get things right here.
The Galaxy Buds are heavily inspired by the AirPods’ simple “just works” approach to the category, bucking Samsung’s tendency to overstuff products. That approach mostly works like a charm on handsets, but the best thing a set of earbuds can do is fade into the background. On that front, the Galaxy Buds work like a charm.
The AirPod comparisons are clear the moment you open the Galaxy Buds case the first time, triggering a dialog box on the screen of your Galaxy device. Like Apple’s version, the headphones will work with any Bluetooth device, but they work best with the company’s own products. Ecosystems, people. For other Android devices, you’ll need to download Samsung’s SmartThings or Galaxy Wearable apps for the proper effect.
The charging case itself is a bit more bulky and bulbous than the AirPods, but it’s certainly small enough to carry around in your jeans pockets. I also actually kind of prefer the pill shape to Apple’s Glide dental floss design.
Rolled out last year as part of a new collection, the Sony wireless in-ear sports headphones are aimed at athletes and other active folks (although there’s absolutely no reason they can’t be your everyday Bluetooth earbuds, too). The Sony wireless headphones are IPX4-rated for water resistance, meaning they’ll hold up just fine to sweat and splashes, and they also come with four sets of earpieces – three standard ones in different sizes as well as one pair of ear hooks for extra in-ear stability – for you to find the perfect fit. With Amazon Prime Day 2019 in a few days, Amazon and Dell have rolled out competitive prices for the wireless headphones.
These Sony wireless in-ear sports headphones are the SP600N model and are an upgrade pick over Sony’s SP500N earbuds. What these ones have that the SP500N lack is active noise-canceling technology (the same found in the fully wireless SP700N which detects exterior sounds and blocks them out so you can enjoy your music or other audio entertainment in privacy. The in-line mic also lets you take and make calls when synced with your phone, and the internal battery runs for up to six hours before needing a charge.
One of the few drawbacks of Bluetooth earbuds (aside from needing to remember to keep them charged up) is their price, as brand-name models can get a bit expensive – a few of our favorites ring in at more than $200. The Sony wireless in-ear sports headphones normally go for $150, which isn’t as bad, but this deal is even sweeter: Dell has them on sale for $100, saving you $50, while Amazon is offering them for a couple bucks less at $98.
In our search for a symphonic solution, I scoured the market reviews and went to my favorite trainers to find out what they use to listen to music during workouts. Below are the results — a mix of headphones and earbuds ranging from higher-end options to more reasonably priced pairs.
Let's start with my favorite headphones. Whether I’m running, working out, or working on the computer, I’ve found that these wireless headphones offer a fantastic audio experience. When I remove them from my ears, the music will stop, and when I place them back in, it starts again seamlessly. The silicone tips are easy to clean, while ear wings tuck into the ear to help keep them in place during workouts.
“I love Aftershokz for running because they use bone conduction tech, so they don’t actually sit in your ears. They sit in front, near your cheekbones, which allows you to hear both your music and outside sounds like cars coming, sirens, and people behind you.” — Amanda Capritto, personal trainer and health coach
“I was worried they’d get slippery with sweat and pop out as I was running down the road. But these buds have stayed put in my ears throughout four-mile runs and at-home dancing sessions. Plus, the sound quality is phenomenal — I always feel like I’m listening to music on a sound system. The best feature: Siri is fully integrated. So, to place a call, play a song, ask for a joke, etc., all I have to do is double tap one of my pods.” — Amelia Pavlik, barre and cycling instructor at Exhale Atlanta
“These earbuds are easy to use, stay put in my ears, and offer more than three hours’ worth of playback time. Plus, they offer a full fitness experience: They connect with the Jabra Sport Life app, which has a built-in heart rate monitor, activity tracker, automatic rep counter, race pace calculator, and more.” — Lynette Pettinicchi, Pilates instructor
“Like our other fixtures, Vivid Pixel is a uniform, direct view light source that is cool to the touch when in operation,” said Derek Breneol, CEO at LED Neon Flex Lighting Solutions. “The difference with Vivid Pixel is that each cutting unit is individually controllable. DMX-512 and Ethernet controls make the product easy to use with any third-party DMX controllers, giving lighting designers full access to advanced chasing and programmable scenes. This advancement opens up a new world of options for lighting designers, and we’re very excited to see what they can do!”
The environmentally friendly and energy-efficient Vivid Pixel LED fixture has an IP68 rating, making it weatherproof. It can be used inside or outside since it functions perfectly in temperatures ranging from -20° to 45° Celsius. Designers may choose from two profiles—a domed 270 degrees or flat 160 degrees. With high color consistency and uniform illumination with no dark spots, the Vivid Pixel LED flex fixture offers an attractive solution. It is suitable for any interior or exterior setting, including concert lighting, stage lighting, theme park attractions and much more.