I used to take centrophenoxine (Lucidril) years ago, before I developed ME/CFS, as a smart drug (nootropic). For me it had similar effects to piracetam, which is another nootropic that works on the acetylcholine system.Centrophenoxine powder

I have not really tried centrophenoxine that much since getting ME/CFS (I did try it in the early years of my ME/CFS, but that was some time ago, and I don't remember what it's effects were on my brain fog).

Piracetam 800 mg is currently my nootropic of choice for reducing brain fog, and it works quite well for me. But I only take it when I really need to concentrate hard on something, because unfortunately I find piracetam creates an undesirable emotional flatness side effect. Other ME/CFS patients have also reported this same emotional flatness side effect of piracetam. Emotional flatness is of course on of the ME/CFS symptoms listed in the CCC, and I suffer from this symptom anyway, so I don't really want anything which exacerbates it.

So perhaps I should try centrophenoxine again, because if it works as well as piracetam, but does not have the piracetam emotional flatness side effects, centrophenoxine would be a useful treatment for brain fog.