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Mapping out a new era in brain research

government funded scheme, recently began trials on healthy volunteers with a state of the art diffusion imaging scanner.

Built by German engineering company Siemens, it works by tracking the passage of water molecules through nerve fibers, giving a more accurate picture of the brain's structure and its neuronal pathways, scientists say.

"The diffusion image replica Van Cleef & Arpels necklace is a map of the water diffusion which we then convert into a marker for the fiber pathways," says Van Wedeen, director of Connectomics at the Martinos Center for Biomedical Imaging at Van Cleef & Arpels White Mother-Of-Pearl necklace replica Massachusetts General Hospital (MGH).

"We then reconstruct it through computer algorithms that explain the water diffusion that we have observed."

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From the outside, the scanner looks like a conventional MRI machine but the power inside enables it to produce images more than 10 times clearer.

"It's the difference between looking at the bonnet (of a car) and looking at the gears and Van Cleef & Arpels Replica Necklace belts inside," Wedeen said.

The idea, he says, is to dispose the brain to a coordinates system.

"Think of the difference of making maps before longitude and latitude versus making maps after," he said.

Data from the scanner is still being refined but Wedeen and his colleague Bruce Rosen are excited about its potential.

"Over time, it's clear that in addition to scanning normal volunteers we'd be very interested in scanning patients with disease," says Rosen, director of the Martinos Center for Biological Imaging at MGH.

"The tools we are developing, as well as many other scientists around the world mapping these brain circuits, may be fundamental to how we understand and conceptualize diseases and treat them," he added.

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