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(finasteride) Film-coated Tablets

PROPECIA (Finasteride powder) tablets contain finasteride as the active ingredient. Finasteride, a synthetic 4-azasteroid compound, is a specific inhibitor of steroid Type II 5α-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT).

The chemical name of finasteride is N-tert-Butyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide. The empirical formula of finasteride is C23H36N2O2 and its molecular weight is 372.55. Its structural formula is:

Finasteride is a white crystalline powder with a melting point near 250°C. It is freely soluble in chloroform and in lower alcohol solvents but is practically insoluble in water.

PROPECIA (finasteride) tablets are film-coated tablets for oral administration. Each tablet contains 1 mg of finasteride and the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate, hydroxypropyl methylcellulose, hydroxypropyl cellulose, titanium dioxide, magnesium stearate, talc, docusate sodium, yellow ferric oxide, and red ferric oxide.
In general, daily use for three months or more is necessary before benefit is observed. Continued use is recommended to sustain benefit, which should be re-evaluated periodically. Withdrawal of treatment leads to reversal of effect within 12 months.

Women should not handle crushed or broken PROPECIA tablets when they are pregnant or may potentially be pregnant because of the possibility of absorption of finasteride and the subsequent potential risk to a male fetus. PROPECIA tablets are coated and will prevent contact with the active ingredient during normal handling, provided that the tablets are not broken or crushed [see WARNINGS AND PRECAUTIONS, Use In Specific Populations and Patient Counseling Information].

Women should not handle crushed or broken PROPECIA tablets when they are pregnant or may potentially be pregnant because of the possibility of absorption of finasteride and the subsequent potential risk to a male fetus. PROPECIA tablets are coated and will prevent contact with the active ingredient during normal handling, provided that the tablets are not broken or crushed [see WARNINGS AND PRECAUTIONS, Use In Specific Populations and Patient Counseling Information].

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

Clinical Studies For PROPECIA (Finasteride 1 mg) In The Treatment Of Male Pattern Hair Loss

In three controlled clinical trials for PROPECIA of 12-month duration, 1.4% of patients taking PROPECIA (n=945) were discontinued due to adverse experiences that were considered to be possibly, probably or definitely drug-related (1.6% for placebo; n=934).

Clinical adverse experiences that were reported as possibly, probably or definitely drug-related in ≥1% of patients treated with PROPECIA or placebo are presented in Table 1.

Sep 12 '19 · 0 comments

Avanafil powder compared to viagra and cialis powder for ed treatment

1.What is Avanafil? Avanafil is used to treat men who have erectile dysfunction (also called sexual impotence). Avanafil powder belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body’s normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, Avanafil powder helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, Avanafil powder will not work to cause an erection.
2.What is Avanafil powder? Avanafil powder raw powder, the material of Avanafil powder, a kind of White powder, many steroids products supplier usually buy high purity Avanafil powder online, make it into all kinds of brand finished Avanafil powder, the detail of the Avanafil powder raw in AAS as below: Name: Avanafil powder CAS: 330784-47-9 Molecular Formula: C23H26ClN7O3 Molecular Weight: 483.95
150-152°C Storage Temp.: RT Color: White powder 3.How Does Avanafil powder Works? Avanafil powder is in a class of medications called phosphodiesterase (PDE) inhibitors.It is used to treat erectile dysfunction (ED: impotence; inability to get or keep an erection in men). This male enhancement product got its name from its main active ingredient which helps the circulation of blood in the body in a normal way. There are other ingredients that makes Avanafil powder effective but don’t have that much impact and effects that its main ingredient has to offer. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil powder does not cure erectile dysfunction or increase sexual desire. Avanafil powder does not prevent pregnancy or
4. the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Avanafil powder is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection), also known as erectile dysfunction (ED). It is in a class of drugs called phosphodiesterase inhibitors that also includes tadalafil (Cialis powder), sildenafil (Viagra) and vardenafil (Levitra). Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, and, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). It is cGMP that is primarily responsible for increasing and decreasing the size of blood vessels carrying blood to and from the penis, respectively, and causing an erection. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the penis, and the erection ends. Avanafil powder prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of cGMP leads to a more prolonged engorgement of the penis with blood. Avanafil powder was approved by the FDA in April 2012. 4.How to Use Avanafil powder? Before taking Avanafil powder  tell your doctor and pharmacist if you are allergic to Avanafil powder, any other medications, or any of the ingredients in Avanafil powder tablets. Ask your pharmacist or check the patient information for a list of the ingredients.  Do not take Avanafil powder if you are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, others). Nitrates come as tablets, sublingual
5. (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are not sure if any of your medications contain nitrates.  do not take street drugs containing nitrates such as amyl nitrate and butyl nitrate (‘poppers’) while taking Avanafil powder.  Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: alpha blockers such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax, in Jalyn), silodosin (Rapaflo), and terazosin; certain antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), and ketoconazole (Nizoral); aprepitant (Emend); clarithromycin (Biaxin, in Prevpac); diltiazem (Cardizem, Cartia, Tiazac); erythromycin (E.E.S, E-Mycin, Erythrocin); HIV protease inhibitors such as atazanavir (Reyataz, in Evotaz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); other medications or treatments for erectile dysfunction; medications for high blood pressure; nefazodone; verapamil (Calan, Covera, Verelan, others); and telithromycin (Ketek).
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with Avanafil powder, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.  tell your doctor if you have ever been advised by a doctor to avoid sexual activity for medical reasons, if you have had heart surgery within the past 6 months and if you have ever had an erection that lasted longer than 4 hours. Also tell your doctor if you have or have ever had a condition that affects the shape of the penis such as angulation, cavernosal fibrosis, or Peyronie’s disease; a heart attack; a stroke; an irregular heartbeat; a blocked artery; angina (chest pain); high or low blood pressure; heart failure; blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); ulcers; bleeding problems; or liver or kidney disease. Also tell your doctor if you have or have ever had retinitis pigmentosa (a rare inherited eye disease) or if you have ever had severe vision loss, especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see.  you should know that Avanafil powder is only for use in males. Women should not take Avanafil powder, especially if they are or may become pregnant or are breastfeeding. If a pregnant woman takes Avanafil powder, she should call her doctor.  talk to your doctor about the safe use of alcoholic beverages during your treatment with Avanafil powder. If you drink a large amount of alcohol (more than three glasses of wine or three shots of whiskey) while you are taking

Sep 12 '19 · 0 comments

Acerus Provides Update On Avanafil Health Canada Submission

Acerus Pharmaceuticals Corporation (TSX:ASP, OTCQB:ASPCF) (“Acerus” or the “Company”) today announced that Health Canada has completed the initial screening process for the previously announced New Drug Submission (“NDS”) for avanafil. The dossier is now in active review by Health Canada and Acerus expects review completion and, if approved, Notice of Compliance issuance to be in early Q2 of 2020.Avanafil powder

Avanafil, a treatment for erectile dysfunction (“ED”), is a new, second generation PDE5 inhibitor, which has increased receptor specificity for fast onset of action and lower off-target side effects.

“We are pleased to report that avanafil is under active review by Health Canada. If approved, avanafil will become a key growth driver of our Canadian men’s health franchise alongside NATESTO®,” said Ed Gudaitis, President and Chief Executive Officer of Acerus. “The product is complementary to the current call point of our Canadian sales team and will allow Acerus to leverage our commercial investment in Canada.

About avanafil

The safety and efficacy of avanafil is supported by four randomized, double-blind, placebo-controlled, parallel trials, which included subjects with erectile dysfunction from either a general ED population, ED patients with diabetes or ED patients following bilateral nerve-sparing radical prostatectomy. In all Phase 3 trials, statistically significant improvement in the primary efficacy measures were observed and were maintained throughout the 8-12-week treatment period. This included statistically significant improvements of +40% to +75% in the erectile function domain of the International Index of Erectile Function (IIEF). Avanafil treatment produced statistically significant increases in vaginal penetration (up to 77%, p<0.01) and successful intercourse (up to 57%, p<0.01). In a trial examining the time-to-onset, avanafil significantly increased the proportion of subjects with successful intercourse as early as 15 minutes and at 6 hours. Avanafil is available in the U.S. under the brand name STENDRA® (avanafil) and is indicated for the treatment of erectile dysfunction. Metuchen Pharmaceuticals LLC (“Metuchen”) has exclusive marketing rights to STENDRA® in the U.S. Acerus licensed avanafil from Metuchen for distribution in Canada.

Sep 12 '19 · 0 comments

Sex hormones Dapoxetine hydrochloride powder,Sexual enhancement Dapoxetine

Synonyms:(aS)-N,N-Dimethyl-a-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine; (S)-(+)--N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine; (1S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (1:1); (1S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine; N,N-dimethyl-3-(2-naphthyloxy)-1-phenyl-propan-1-amine.

Molecular Weight: 305.4134

Molecular Formula: C21H23NO

Density: 1.081g/cm3

Boiling Point(°C): 454.4°C at 760 mmHg

Flash Point(°C): 132.6°C

refractive_index: 1.607

Dapoxetine Hydrochloride powder,Dapoxetine HCL powder is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18–64 years old.Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay.As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.

Sep 12 '19 · 0 comments

Adidas Yeezy Boost 350 V2 "Black" To Restock This Fall: Details

If you're a big fan of the Yeezy brand and more specifically, the Adidas Yeezy Boost 350 V2, then you know all about the "Black" colorway that finally released this Summer. After years of asking for a black model, Kanye West delivered on the fans wishes and the shoe was a big success. Since the shoe was so high in demand, not everyone who wanted them got a pair which led to some pretty hefty resale prices. If you want to buy these on a resale website like StockX, you would have to pay over double the retail cost.

According to Yeezy Mafia, those who missed out on the first drop will get a second shot at copping this beautiful shoe. Yes, that's right, just like many other Yeezy models, the "Black" 350 V2 will be getting a restock. This restock will include full family sizing and will happen on Friday, November 29th, otherwise known as "Black Friday." The adult version will cost $220 USD and will certainly be a great addition to your collection.

So far, there is no word on how limited they will be but expect some difficulties copping. Stay tuned for updates as we will be sure to bring them to you closer to the release date.get Yeezy 350 Static Cheap,more order with big discount

Sep 9 '19 · 0 comments

The adidas Yeezy Boost 350 v2 “Black” Will Return On Black Friday

One of the most popular adidas Yeezys to date, the adidas Yeezy Boost 350 v2 “Black” was a massive success when it quickly sold out upon its initial release this June, and now it’s set to come back for the holiday season, as it’ll be restocking on Black Friday. Garnering acclaim for its simple-yet-effective look, the monochromatic Yeezy 350 offered all the signature textured detailing and translucent side striping that fans of Kanye West‘s adidas shoes have come to know and love, but dressed it entirely in black for a versatile look. Flecked laces and a pop of red on the heel tab provided nods to the classic adidas Yeezy Boost 350 “Pirate Black” that first released back in 2015, while a semi-translucent midsole packed full of Boost cushioning rounded off the styling. The restock will be going down in full family sizes — men’s pairs retail at $220 USD, kids at $160 USD and infants at $140 USD — on November 29th (Black Friday), so stay tuned for more info as the annual day of shopping draws closer.buy Cheap Yeezy 350 Glow with best price

Sep 9 '19 · 0 comments

Gabapentin and pregabalin become class C drugs

An expert in mental health and addiction at the University of York comments on the Government's move to make gabapentin and Buy Pregabalin powder a class C drug.

Ian Hamilton, from the University of York's Department of Health Sciences, said: "From today (Monday, 1st of April), gabapentin and pregabalin will become class C drugs in a move that the Government hopes will stem the significant rise in problems associated with these drugs.

"In the last five years prescriptions for pregabalin have increased by 350 percent and by 150 percent for gabapentin. These drugs are licensed for the treatment of epilepsy, anxiety and pain but there has been a significant rise in deaths due to these drugs and people developing problems with physical and psychological dependency.

"This is not the first time that the Home Office has tried to reduce the harm associated with the misuse of medication; in 2014 they made Tramadol a class C drug following similar concerns about increasing prescriptions and mortality.Although this policy move appeared to be successful as deaths and prescriptions for Tramadol have reduced it is likely that this has merely moved the problem onto other drugs like gabapentin and pregabalin.

"People use these drugs to self-medicate for a range of psychological and social problems which they are unable to get help and support for, as specialist drug treatment and mental health services become harder to access due to funding cuts year-on-year.

"So we shouldn't be surprised when people find solutions to their problems through drugs which don't have waiting lists or ask probing questions. Although these drugs might alleviate unwanted feelings and emotions in the short term, they are risky and not a long-term solution.

"Equally, the Government's response of restricting access to these drugs in the hope it will reduce harm is naïve; as we can't stop suffering, people will simply find an alternative drug to ease their pain.

Sep 9 '19 · 0 comments

Testosterone Phenylpropionate Results

Buy Testosterone phenylpropionate powder is a quick release form of testosterone, causes greatfluctuations in hormone levels that is appreciated by bodybuilders for quickly increasing muscle size and strength, but the downside is that the fast muscle gain disappears within a few weeks after the drug is discontinued.
As a hormone, it can have an impact on numerous body functions, not only involving the endocrine system, but the metabolism. It also has an impact on cholesterol levels, which any anabolic steroid can.
As such it has the potential to interfere with the body’s ability to regulate levels ofgood (HDL – high density lipoprotein) and bad (LDL – low density lipoprotein) cholesterol.

Dosing information mentions that the average dose for men can be anywhere between 125 and 300 mg twice weekly with cycling every five to eight weeks.Testosterone Phenylpropionate powder exhibits a short half-life, with efficacy that lasted about four days.
Use of the drug typically causes an increase of levels in the blood within about sixhours, and the effect lasts between three and four days.

Sep 9 '19 · 0 comments

What is Nolvadex? How does it work?

At the moment, breast cancer is one of the most prevalent illnesses that women suffer from. Lots of research have been done and is still being done on drugs that could help one live a cancer-free life. Buy Nolvadex powder (54965-24-1) is one of the treatments that have proven to be beneficial in the prevention and treatment of breast cancer. Other than that its affordability earns it a place in the global stage.

Nolvadex (54965-24-1) is an oral pill that has been effective in the treatment of patients who have advanced stage cancer. It was discovered in 1966, and its study as a cancer treatment drug started in 1970. In 1998, it became the first drug to get approval from the FDA to help prevent breast cancer. Research done showed that Nolvadex reduced the chances of suffering from breast cancer by 50% for females who were at a high risk of developing it.

To understand how Nolvadex works, you ought to know that breast cancer cells require a female hormone known as estrogen to grow and multiply. Tamoxifen is, therefore, able to curb this by competing with estrogen in binding to estrogen receptors in the breast cancer cells.

Nolvadex (54965-24-1) is formally referred to as a selective estrogen receptor modulator (SERM). It, therefore, reduces the growth and reproduction of breast cancer cells by blocking estrogen in the breast.

Other than Nolvadex fighting estrogen in breast cancer cells, it also copies the positive effects that estrogen causes in the body system. For postmenopausal women who are on tamoxifen, it may decrease the risk of heart disease as well as osteoporosis (a condition that causes that leads to wasting of the bones) without having to undergo hormone replacement therapy.

2. Nolvadex uses aasraw

Nolvadex has been in use since ages in the treatment of various conditions. It comes as a savior with the vast majority of men and women suffering from such illnesses at least once in their lifetime. Here are some of the Nolvadex uses that have made it stand out;

Nolvadexmay be prescribed in both men and women as treatment of lymph node positive or lymph node-negative breast cancer after they have had a successful surgery. Nolvadex use has proven to be more beneficial when dealing with cancer that has positive estrogen and progesterone receptors. Nolvadex lowers the risk of cancer transferring to the opposite breast.
Men and women who have metastatic breast cancer (cancer that has spread) may be prescribed with Nolvadex.
Women who suffer from ductal carcinoma in situ (DCIS) and who have already undergone surgery and radiation therapy may benefit from this drug too. In this case, Nolvadexmay decrease the risk of suffering from invasive breast cancer. The risk and benefit of having this treatment should, however, be discussed beforehand.
Women who are at a high risk of developing breast cancer could also be prescribed with the drug to help counter the possibility of having it. The risks and benefits of having this treatment should, however, be discussed in this case.One of the uncommon Nolvadex usesin the treatment of ovarian cancer.

Sep 9 '19 · 0 comments

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Sep 9 '19 · 0 comments
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