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The binding of Nexium to human plasma proteins is approximately 20%,
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which may affect the therapeutic response (see PRECAUTIONS - Drug Interactions). Nexium and its metabolites are excreted primarily in he urine with observed plasma half-lives of 6.3 and 7.4 hours for Nexium and M1, respectively.
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causing mental or physical dependence.It works in certain areas of the brain and nervous system to decrease pain.
Forty patients were treated with either Nexium suppositories 100 mg 6 hourly.
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For Nexium, the following should be considered:The suitability of Nexium suppositories for inclusion in our hospital formulary for the treatment of mild to moderate post-operative pain was evaluated.
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Do not use this medication if you are allergic,
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Nexium is administered as a racemate and both [-] and [+] forms of both Nexium and M1 are detected in the circulation.
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Nexium may rarely be habit forming. Nexium should be avoided in patients with a history.
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Talk with your doctor if Nexium stops working well. Do not take more than prescribed.Some people who use Nexium for a long time without a break may develop a physical need to continue taking it.
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Linear pharmacokinetics have been observed following multiple doses of 50 and 100 mg to steady-state.Racemic Nexium is rapidly and almost completely absorbed after oral administration.
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Nexium has not been shown to cause histamine release. At therapeutic doses, Nexium has no effect on heart rate, left-ventricular function or cardiac index.
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1 Dosing may be increased to 100 mg every four to six hours, but the daily dosage should not exceed 400 mg 1 and should be limited to 250 to 300 mg .
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the rates of withdrawals due to adverse events appeared to be higher in the Nexium groups.
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Forty patients were treated with either Nexium suppositories 100 mg 6 hourly.
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