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Nexium has not been shown to cause histamine release. At therapeutic doses, Nexium has no effect on heart rate,
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Nexium should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
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which may affect the therapeutic response (see PRECAUTIONS - Drug Interactions). Nexium and its metabolites are excreted primarily in he urine with observed plasma half-lives of 6.3 and 7.4 hours for Nexium and M1, respectively.
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In general, both enantiomers of Nexium and M1 follow a parallel time course in the body following single and multiple doses although small differences (~10%) exist in the absolute amount of each enantiomer present.
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How does Nexium work? What will it do for me?Nexium can cause side effects that may impair your thinking or reactions.

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Nexium and M1 elimination half-lives (13 hrs. for Nexium and 19 hrs. for M1).
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