Triptorelin Injection

Triptorelin Acetate powder injection (Trelstar) is used to treat the symptoms associated with advanced prostate cancer. Triptorelin injection (Triptodur) is used to treat central precocious puberty (CPP; a condition causing children to enter puberty too soon, resulting in faster than normal bone growth and development of sexual characteristics) in children 2 years and older. Triptorelin injection is in a class of medications called gonadotropin-releasing hormone (GnRH) agonists. It works by decreasing the amount of certain hormones in the body.

Triptorelin injection (Trelstar) comes as an extended-release (long-acting) suspension to be injected into the muscle of either buttock by a doctor or nurse in a medical office or clinic. Triptorelin injection (Trelstar) also comes as an extended-release suspension to be injected into the muscle of the buttock or thigh by a doctor or nurse in a medical office or clinic. When used for prostate cancer, an injection of 3.75 mg of triptorelin (Trelstar) is usually given every 4 weeks, an injection of 11.25 mg of triptorelin (Trelstar) is usually given every 12 weeks, or an injection of 22.5 mg of triptorelin (Trelstar) is usually given every 24 weeks. When used in children with central precocious puberty, an injection of 22.5 mg of triptorelin (Triptodur) is usually given every 24 weeks.

Triptorelin may cause an increase in certain hormones in the first few weeks after injection. Your doctor will monitor you carefully for any new or worsening symptoms during this time.
Before receiving triptorelin injection,

tell your doctor and pharmacist if you are allergic to triptorelin, goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron), nafarelin (Synarel), any other medications, or any of the ingredients in triptorelin injection. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Nexterone, Pacerone); bupropion (Aplenzin, Wellbutrin, Zyban); carbamazepine (Tegretol, Teril, others); methyldopa (in Aldoril); metoclopramide (Reglan); reserpine, or selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac, Sarafem), sertraline (Zoloft), and paroxetine (Paxil). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you or anyone in your family has ever had long QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause fainting or sudden death). Also tell your doctor if you have or have ever had diabetes; cancer that has spread to the spine (backbone),; urinary obstruction (blockage that causes difficulty urinating), a low level of potassium, calcium, or magnesium in your blood, a heart attack; heart failure; a mental illness; a seizure or epilepsy; a stroke, mini-stroke, or other brain problems; a brain tumor; or heart, kidney, or liver disease.
you should know that triptorelin is not to be used in women who are pregnant or who can become pregnant. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you think you have become pregnant while using triptorelin injection, call your doctor immediately. Triptorelin injection can harm the fetus.