how does Pikamilone sodium powder workThe benefits of Picamilon may help individuals with anxiety, depression, sleep disorders or other mood disorders. Picamilon is used by individuals who who want to increase focus and mental energy without higher levels of anxiety.

Many people use Picamilon to help them overcome stress and shyness in social settings. It is reported by some to help stop you from dreading these kinds of interactions by lowering inhibitions.

This nootropic is most often compared to Phenibut which is also a GABAergic anti-anxiety supplement, but the biggest difference is that Phenibut has a sedative effect whereas Picamilon does not.

How Does Picamilon Work?

Picamilon is transported across the blood-brain barrier by a special niacin analog pathway.

It is then hydrolyzed (reacted with water) and broken down into the neurotransmitter GABA and niacin. From here, the effects produced by Picamilon are typical of higher levels of GABA and niacin.

GABA is considered an inhibitory neurotransmitter, used by your brain to promote relaxation and prevent over-stimulation. These effects are described as anxiolytic meaning that they reduce anxiety and stress.

Many people experience a tranquil and easy-going state of mind when taking GABAergic compounds like Picamilon. You may also feel a lowering of inhibitions which inhibit feelings of social anxiety.

Picamilon is reported to help switch off some of the incessant "mind chatter" or background noise in the brain that can disrupt thought patterns and prevent you from being able to focus.
Picamilon is a molecular combination of vitamin B3 and γ-aminobutyric acid (GABA). Picamilon was reported to decreases cerebral blood-vessel tone and increases intracranial circulation rate. The drug exceeds in forceand duration the effects of GABA and niacin alone. In small doses, Picamilon shows tranquilizing action to prevent the negative effects of emotional stress. The tranquilizing influence of the drug on negative emotions expressed through the hypothalamic system has been proved. Picamilon is characterized by a tranquilizing effect, without a sedative component but with elements of stimulant action. The drug effectively counteracts stress and lowers the depressing influence of ethanol on the behavior of animals. It rapidly penetrates through the blood-brain barrier and improves the functional state of the brain by producing a beneficial effect on its metabolism. Due to its GABA affiliation picamilon also acts as a mild sedative, calming the nerves and reducing symptoms of anxiety and irritability.