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Copegus is an antiviral drug. It is used in combination with interferon for the treatment of chronic hepatitis C. Copegus monotherapy is not effective for the treatment of chronic hepatitis C virus infection and should not be used alone for this indication. It works by helping the immune system fight the hepatitis C virus, and by making it harder for the virus to reproduce within the body. It is therefore necessary to consider an earlier reduction in the ribavirin dose in such patients to prevent discontinuation of treatment because of anemia. ... However, because red blood cells lack dephosphorylation enzymes, ribavirin accumulates in cells and destroys the cells, causing hemolytic anemia.

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