We are leading Adhesive tape-making machine manufacturers in India. Our offered machines are manufactured by our skilled professionals using the best technology in the manufacturing sector to render maximum client satisfaction. The offered machine is designed and developed following industry standards and is carefully tested by our quality specialists to ensure compliance with international manufacturing standards. It works extremely quickly and precisely, applying uniform films that satisfy the needed criteria. They offer outstanding automated functions and customizable computerized controls, making them suitable for a wide range of applications.Get more news about Oral Disintegrating Film Making Machine,you can vist our website!

Cello Tape Machine plant manufactured by us has added a new dimension to the packaging. We make use of bi-axially or cello self adhesive tape plant manufactured by us has added a new dimension to the packaging. We make use of bi-axially oriented polypropylene film which has superior adhesive is applied by using latest coating machine. These adhesives last longer and provide internal molecular strength and elasticity due to its cross directional orientation. Oriented polypropylene film which has superior adhesive is applied by using latest coating machine. These adhesives last longer and provide internal molecular strength and elasticity due to its cross directional orientation. Our tape making machine is highly recognised among the customers.

When working the screen changer, the machine doesn't stop and keep working.
The film can be increased strongly and transparently, when it passes through the hot water bath and the heating blower.
The film bag is easy to slit in the auxiliary take-off unit with slitting device.
After the film bags become the strips; it is strong and tenacious after heated and stretched by heating bridge.
The strips are easy to disassemble from the winding unit.
We are the professional manufacturer and experience supplier for light packing tape making plant.

A number of viable methods exist for the production of ODFs. Hot-melt extrusion is one of the most recommended of these as a continuous process with good reproducibility which is effective without the need for added solvents.Get more news about Oral Disintegrating Film Making Machine,you can vist our website!

It is possible to manufacture high quality ODFs at either a lab or production scale with the help of Thermo ScientificTM pharmaceutical extruders and down-stream equipment.Two of the most common methods of production for ODFs are solvent casting and hot-melt extrusion (HME)1. For initial studies and excipient screening, solvent casting is a frequently selected option. However, while it is highly appropriate for thermolabile APIs, it does require the use of a solvent and problems may be experienced during scale-up.

An improved alternative exists in HME. Unlike solvent casting, HME is an environmentally friendly technology with no need for solvents. It offers high reproducibility, as well as demonstrating superior uniformity of content with a lower number of production stages and decreased costs2.

In addition to this, with HME, API and excipients are mixed on a molecular level, which leads to a more uniform dispersion of the API in the ODF, subsequently increasing the drug's bioavailability.

Scale-up in HME has been well established4, and is easily carried out with Thermo Scientific extruders. With an appropriate choice of excipients, HME is the most highly recommended method for pioneering ODF formulation2.HME is a well understood and established method of production which has a lengthy history in plastic and food processing and is experiencing increasing popularity in the pharmaceutical industry. Pharmaceutical formulations for HME typically consist of combinations of API, polymers and largely, plasticizers or other excipients.

HME works by melting the polymer in a twin-screw extruder. All ingredients are mixed together and kneaded. As such, intense compounding occurs. The die is positioned at the end of the twin-screw extruder and dictates the shape of the extrudate. The melt is squeezed through the hole in the die.

Additional continuous processing can be provided by down-stream equipment, including conveyors, pelletizers or take-off systems and cutters. With HME granules, it is possible to produce tablets with a modified drug release profile, in addition to transdermal, transmucosal or subcutaneous drug delivery systems3.

A sheet-die is employed to determine the width and thickness of the film for the production of ODFs. Since the majority of pharmaceutical polymers are somewhat brittle, it is vital that appropriate plasticizing excipients are chosen.The extruded film should be flexible and stretchable. The extruded film is pulled at a fixed speed to ensure a homogenous thickness, with the help of a take-off and wind-up system.

A standard benchtop system (Figure 1) is comprised of a gravimetric twin-screw feeder which feeds the pre-blended material into a Thermo ScientificTM Pharma 11 Twin-Screw Extruder. The extruded film is continuously pulled by the sheet take-off. To finish, the film is wound up on a roll (Figure 2).

This process allows thin films to be produced at a consistent thickness of 100 μm. Adjusting the slit of the sheet die, alongside the pulling speed and throughput, allows for alteration of the thickness of the film.