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Nexium has not been shown to cause histamine release. At therapeutic doses, Nexium has no effect on heart rate, left-ventricular function or cardiac index.
causing mental or physical dependence.It works in certain areas of the brain and nervous system to decrease pain.
Nexium can increase the risk of seizure in epileptic patients, especially with simultaneous use of tricyclic antidepressants,
clinical trial was performed to assess the analgesic efficacy and reported side effects of Nexium 100 mg, Nexium 50 mg,
You may not be able to take Nexium, or you may require a dosage adjustment,
since observed maximal placoncentrations after multiple oral doses are higher than expected based on single-dose data.
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Nexium has been shown to inhibit reuptake of norepinephrine and serotonin in vitro,
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Nexium had only slight thermoregulatory effects. Its use is thus unlikely to provoke hypothermia or to facilitate fever.
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Nexium is found in breast milk. Do not breast-feed while taking Nexium .When used for long periods of time or at high doses,
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risk of discontinuation due to adverse events associated with higher initial doses,
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which may affect the therapeutic response (see PRECAUTIONS - Drug Interactions). Nexium and its metabolites are excreted primarily in he urine with observed plasma half-lives of 6.3 and 7.4 hours for Nexium and M1, respectively.
Nexium has a volume of distribution of approximately 2.7 L/kg and is only 20% bound to plasma proteins.
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Nexium may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE.
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Intramuscular (i.m.) Nexium increases gastric pH during anaesthesia similar to famotidine.
The binding of Nexium to human plasma proteins is approximately 20%,
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Ask your pharmacist if you have questions about which medicines may cause drowsiness.Nexium may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect.
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