Apollo's Hegemony Synephrine is a dietary supplement containing synephrine hydrochloride – a natural compound that effectively promotes fat loss and weight loss. One capsule contains 20 mg synephrine hydrochloride. The product is suitable for vegans and vegetarians.

Synephrine is an alkaloid naturally occurring primarily in the peel of a bitter orange (Citrus aurantium), as a para isomer (p-synephrine) (p-synephrine should be distinguished from m-synephrine, i.e. phenylephrine). Originally, synephrine was synthesized as a sympathomimetic drug, demonstrating a structural similarity to ephedra and adrenaline.

The mechanism of action of p-synephrine
P-synephrine has sympathomimetic effects, which means that it stimulates adrenergic receptors. It is an agonist of β-adrenergic receptors and most likely an antagonist of α1- and α2-adrenergic receptors.

These receptors are naturally stimulated by adrenaline and noradrenaline and play an important role in the regulation of energy processes, optimal blood glucose concentration, and metabolic rate. The sympathomimetic activity of p-synephrine is responsible for the multidirectional effect of the compound on the loss of body weight and body fat.
P-synephrine dispalys a multi-directional effect towards fat burning.. Due to the influence on β3-adrenergic receptors located in fat tissue, p-synephrine has thermogenic properties, which means that it increases heat production in the body. This is done at the expense of increasing the energy expenditure and most often the need to use energy reserves of the body, i.e. adipose tissue. In addition, activation of the β3 receptor increases the lipolysis process.raw Synephrine powder

Impact on metabolism
The effect of the activity of p-synephrine is the acceleration of the metabolic rate. This compound affects the increase of the basic metabolism, defined as the minimal caloric demand of the body. This makes it easier to achieve the caloric deficit necessary to lose weight. In addition, p-synephrine stimulates glycogenolysis, glycolysis, gluconeogenesis and increases oxygen uptake.