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Betaxolol is well absorbed orally with an absolute bioavailability of 75%. Betaxolol has a volume of distribution of approximately 2.7 L/kg and is only 20% bound to plasma proteins.
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than your doctor tells you to.Despite not being labeled habit-forming,
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Betaxolol is found in breast milk. Do not breast-feed while taking Betaxolol .When used for long periods of time or at high doses,
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Although Betaxolol is known to exhibit a local anaesthetic effect, how Betaxolol exerts this effect is not understood fully.
Nonetheless, Betaxolol nearly doubled the interthreshold range at a concentration near 200 ng/mL.
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Betaxolol can increase the risk of seizure in epileptic patients, especially with simultaneous use of tricyclic antidepressants,
Betaxolol may not work as well and may require higher doses to obtain the same effect as when originally taken.
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which may affect the therapeutic response (see PRECAUTIONS - Drug Interactions). Betaxolol and its metabolites are excreted primarily in he urine with observed plasma half-lives of 6.3 and 7.4 hours for Betaxolol and M1, respectively.
Nalbuphine consumption in the first 24 h after operation was reduced by 35% in the Betaxolol group.
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The effects of Betaxolol and its metabolite mono-O-demethyl-Betaxolol,
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In general, both enantiomers of Betaxolol and M1 follow a parallel time course in the body following single and multiple doses although small differences (~10%) exist in the absolute amount of each enantiomer present.
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Betaxolol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Betaxolol was not mutagenic in the following assays: Ames Salmonella microsomal activation test,
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No effects on fertility were observed for Betaxolol at oral dose levels up to 50 mg/kg,
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Betaxolol is well absorbed orally with an absolute bioavailability of 75%. Betaxolol has a volume of distribution of approximately 2.7 L/kg and is only 20% bound to plasma proteins.
Racemic Betaxolol is rapidly and almost completely absorbed after oral administration.
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The analgesic activity of Betaxolol is due to both parent drug and the M1 metabolite (see CLINICAL PHARMACOLOGY, Pharmacodynamics).
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Check the label on the medicine for exact dosing instructions.Betaxolol may cause drowsiness and dizziness.
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Do not use this medication if you are allergic,
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Betaxolol was not mutagenic in the following assays: Ames Salmonella microsomal activation test,
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Betaxolol was one of the more important gods in the Rig Veda; 120 hymns and one entire book.
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