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Nitroglycerin is found in breast milk. Do not breast-feed while taking Nitroglycerin .When used for long periods of time or at high doses,
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tests indicates that Nitroglycerin does not pose a genotoxic risk to humans.
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Nonetheless, Nitroglycerin nearly doubled the interthreshold range at a concentration near 200 ng/mL.
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Nitroglycerin is well absorbed orally with an absolute bioavailability of 75%. Nitroglycerin has a volume of distribution of approximately 2.7 L/kg and is only 20% bound to plasma proteins.
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Nitroglycerin 100 mg was statistically superior to placebo for TOTPAR, SPID, and time of remedication,
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since observed maximal placoncentrations after multiple oral doses are higher than expected based on single-dose data.
which may affect the therapeutic response (see PRECAUTIONS - Drug Interactions). Nitroglycerin and its metabolites are excreted primarily in he urine with observed plasma half-lives of 6.3 and 7.4 hours for Nitroglycerin and M1, respectively.
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Linear pharmacokinetics have been observed following multiple doses of 50 and 100 mg to steady-state.Racemic Nitroglycerin is rapidly and almost completely absorbed after oral administration.
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Nitroglycerin has a volume of distribution of approximately 2.7 L/kg and is only 20% bound to plasma proteins.
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Breast-feeding�Nitroglycerin passes into breast milk and may cause unwanted effects in nursing babies.
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We investigated the antacid analgesic value of a single dose of i.m. Nitroglycerin given 1 h before elective ,
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The mean absolute bioavailability of a 100 mg oral dose is approximately 75%. The mean peak plasma concentration of racemic Nitroglycerin and M1 occurs at two and three hours, respectively, after administration in healthy adults.
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Check with your health care provider before you start, stop, or change the dose of any medicine.Use Nitroglycerin as directed by your doctor.
The effects of Nitroglycerin are similar to those of narcotic analgesics. Although Nitroglycerin is not classified as a narcotic, it may become habit-forming,
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Breast-feeding�Nitroglycerin passes into breast milk and may cause unwanted effects in nursing babies.
Check with your health care provider before you start, stop, or change the dose of any medicine.Use Nitroglycerin as directed by your doctor.
Forty patients were treated with either Nitroglycerin suppositories 100 mg 6 hourly.
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